Alloantigen System L Affects Antibody Responses
نویسندگان
چکیده
منابع مشابه
Immunochemical Characterization of the Platelet - Specific Alloantigen Lek 5 : A Comparative Study With the l ’ ’ Alloantigen
We report the immunochemical characterization of a new platelet-specific alloantigen detected using an lgG antibody isolated from the serum of a patient with posttransfusion purpura (PTP). In indirect immunoprecipitation experiments, the antibody, termed anti Leka, predominantly precipitated glycoprotein (GP) llb from Triton X-100 lysates of normal human platelets. In an immunoblot procedure, w...
متن کاملGova/b alloantigen system on human platelets.
In this report we describe a platelet alloantigen system that is carried on a novel platelet protein of 175 Kd. Antisera against the two alleles (Gova/Govb) were found in two patients who had received large numbers of platelet transfusions. The anti-Gov alloantibodies could not be detected using a whole platelet solid phase enzyme immunoassay, or by a platelet glycoprotein capture enzyme immuno...
متن کاملSuppressive mechanisms in alloantigen-induced T cell responses
In this report we examined the possibility that suppression of the mixed lymphocyte response by MLR-TsF results from interference with IL-2 regulation of T cell proliferation. Two distinct processes of inhibition involving both a direct effect on IL-2-driven proliferation of responder T cells, and induction of a second-order suppressor cell (Ts2) were described. Exogenous IL-2 did not abrogate ...
متن کاملThe Bra/Brb alloantigen system on human platelets.
Anti-Bra was first identified in four cases of neonatal alloimmune thrombocytopenia (NAIT). The antigen Bra is localized on the glycoprotein Ia/IIa complex of platelets. Anti-Bra can best be detected by a glycoprotein-specific immunoassay using monoclonal antibodies for antigen immobilization (MAIPA assay) and radioimmunoprecipitation (RIP). Recently, we have identified sera from two polytransf...
متن کاملExtrafollicular antibody responses.
In adaptive antibody responses, B cells are induced to grow either in follicles where they form germinal centers or in extrafollicular foci as plasmablasts. Extrafollicular growth typically occurs in the medullary cords of lymph nodes and in foci in the red pulp of the spleen. It is not a feature of secondary lymphoid tissue associated with the internal epithelia of the body. All types of naïve...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Poultry Science
سال: 2002
ISSN: 1682-8356
DOI: 10.3923/ijps.2003.23.27